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The most powerful force on earth is about to be unleashed by the two people who should know better.

10 years after the events of the first film, Rick O'Connell (Brendan Fraser) is now married to Evelyn (Rachel Weisz) and the couple has settled in London, where they are raising their 8-year-old son Alex. When a chain of events finds the corpse of Imhotep resurrected in the British Museum, the mummy Imhotep walks the earth once more, determined to fulfill his quest for immortality. But another force has also been set loose in the world... one born of the darkest rituals of ancient Egyptian mysticism, and even more powerful than Imhotep. When these two forces clash, the fate of the world will hang in the balance, sending the O'Connells on a desperate race to save the world from unspeakable evil, and rescue their son before it is too late...